*Direct Oral Anticoagulant (DOAC).
†CAD=coronary artery disease.

What is XARELTO®?

XARELTO® belongs to a group of medicines called direct oral anticoagulants, or DOACs  for short. Like other DOACs, XARELTO® has no known dietary restrictions and no requirements for frequent blood tests.

Risk factors image

XARELTO®, in combination with low-dose aspirin,‡ is the only drug in its class§ indicated to help reduce the risk of heart attack, stroke, or cardiovascular death in adults
with CAD.

96%

In fact, in a clinical trial, almost 96% of adults with CAD taking XARELTO® 2.5 mg twice daily, in combination with low-dose aspirin, did not have a heart attack, stroke, or die from a cardiovascular event.||

Remember, all blood thinners come with a risk of bleeding. Around 3% of people taking XARELTO® 2.5 mg twice daily in combination with low-dose aspirin experienced a major bleeding event, such as bleeding into the brain, compared to around 2% of people taking low-dose aspirin alone.

‡Low-dose aspirin = 75 mg–100 mg once daily.

§Direct Oral Anticoagulant (DOAC).

||The rate of the first event like a stroke, heart attack, or cardiovascular death was 4.2% for people taking XARELTO® plus aspirin vs 5.6% for aspirin alone. Patients were followed for an average of 23 months.

Take one XARELTO® 2.5 mg tablet twice daily with or without food in combination with low-dose aspirin (75 mg-100 mg) once daily

Tablet

Tablets shown not actual size

How do you take XARELTO®?

  • Take XARELTO® 2.5 mg twice daily with or without food in combination with aspirin 75 mg–100 mg once daily as instructed by your healthcare professional
  • If you miss a dose of XARELTO®, take your next 2.5 mg dose at your regularly scheduled time
  • Remember, there are no known dietary restrictions, unlike warfarin (Coumadin®)

Are there any side effects associated with XARELTO® in adults?

Side effects of XARELTO®:

  • Increased risk of bleeding
    • You are likely to bruise more easily and it may take longer for the bleeding to stop

Your risk of bleeding increases if you take XARELTO® with other medicines that also increase your risk of bleeding, such as:

    • Aspirin or aspirin-containing products
    • Long-term (chronic) use of non-steroidal anti-inflammatory drugs (NSAIDs)
    • Warfarin sodium(Coumadin®, Jantoven®)
    • Any medicine that contains heparin
    • Clopidogrel (Plavix®)
    • Selective serotonin reuptake inhibitors (SSRIs)
    • Serotonin norepinephrine reuptake inhibitors (SNRIs)
    • Other medicines to prevent or treat blood clots
getting started

Getting started with XARELTO®?

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