*EINSTEIN DVT/PE, EINSTEIN CHOICE, MAGELLAN, and RECORD1-3.
†DVT=deep vein thrombosis, PE=pulmonary embolism.
†Direct Oral Anticoagulant (DOAC).

What is XARELTO®?

XARELTO® belongs to a group of medicines called direct oral anticoagulants, or DOACs for short. Like other DOACs, XARELTO® has no known dietary restrictions and no requirements for frequent blood tests.

Treats DVT and PE

In two clinical studies, almost 98% of adults being treated for a DVT or PE with XARELTO® did not have another one.§

§2.1% of patients treated with XARELTO® experienced another DVT vs 3.0% of patients treated with enoxaparin/vitamin K antagonist (EINSTEIN DVT). 2.1% of patients treated with XARELTO® experienced another PE vs 1.8% of patients treated with enoxaparin/vitamin K antagonist (EINSTEIN PE). Patients were followed for an average length of 208 days. People taking XARELTO® to treat a DVT or PE showed a major bleeding rate of 1% with XARELTO® vs 1.7% with enoxaparin and vitamin K antagonist.

Reduces the risk of another DVT and PE from happening again

In another clinical study, almost 99% of adults taking XARELTO® did not have another DVT or PE after 6 months of initial treatment for blood clots.||

||XARELTO® was superior to aspirin in reducing the risk of DVT/PE. After receiving treatment for blood clots for at least 6 months, 1.2% of patients on XARELTO® experienced another DVT or PE vs 4.4% on aspirin at 1 year (EINSTEIN CHOICE). Less than 1% of patients taking XARELTO® experienced major bleeding, which is similar to the rate of major bleeding in patients taking aspirin to reduce their risk of recurrent DVT or PE.

Talk to your doctor

Talk to your doctor about XARELTO®

Use this guide to discuss the risks associated with having another PE with your doctor, and whether XARELTO® may be right for you.

Start a Doctor Discussion Guide

dosing new

How do you take XARELTO®?

For DVT or PE, take XARELTO® 1 or 2 times a day as prescribed by your doctor

  • If your doctor prescribed the 10-mg dose, take XARELTO® with or without food
  • If your doctor prescribed the 15-mg or 20-mg dose, take XARELTO® with food at the same time each day
  • If you take XARELTO® twice a day and miss a dose, take it as soon as you remember on the same day. You may take 2 doses at the same time to make up for the missed dose. Take your next dose at your regularly scheduled time
  • If you take XARELTO® once a day and miss a dose, take it as soon as you remember on the same day. Take your next dose at your regularly scheduled time
  • Do not change your dose or stop taking XARELTO® unless your doctor tells you to. Your doctor may change your dose if needed
  • Remember, there are no known dietary restrictions, unlike warfarin (Coumadin®)

Are there any side effects associated with XARELTO® in adults?

Side effects of XARELTO®:

  • Increased risk of bleeding
    • You are likely to bruise more easily and it may take longer for the bleeding to stop

Your risk of bleeding increases if you take XARELTO® with other medicines that also increase your risk of bleeding, such as:

    • Aspirin or aspirin-containing products
    • Long-term (chronic) use of non-steroidal anti-inflammatory drugs (NSAIDs)
    • Warfarin sodium (Coumadin®, Jantoven®)
    • Any medicine that contains heparin
    • Clopidogrel (Plavix®)
    • Selective serotonin reuptake inhibitors (SSRIs)
    • Serotonin norepinephrine reuptake inhibitors (SNRIs)
    • Other medicines to prevent or treat blood clots

Always tell your healthcare professional if you experience any side effects while taking
XARELTO® —keeping an open and honest conversation going with your healthcare professional will help you get the best care. You can use the Doctor Discussion Guide to help inform your conversation.